GTA IV isn’t just remembered for its gritty storyline and immersive world — it’s also packed with unforgettable missions that defined a new era of open-world storytelling. Here are the most iconic missions from GTA IV that players still talk about to this day.
1. Three Leaf Clover
This mission is often referred to as the first true heist in the Grand Theft Auto series. Inspired by classic crime films like Heat, it features an intense bank robbery followed by a dramatic shootout and getaway through the subways of Liberty City. A fan favorite for a reason!
2. Out of Commission / A Revenger’s Tragedy (Final Mission)
The final mission offers players a choice between revenge and a deal, each leading to a different ending. The emotional weight, combined with the high-octane action, makes this one of the most memorable conclusions in gaming history.
3. The Holland Play
This mission forces you to choose between two characters: Playboy X or Dwayne Forge. Your decision has permanent consequences, making players truly feel the moral weight of their actions.
4. Museum Piece
A dramatic shootout in the heart of a museum, this mission features multiple betrayals, double-crosses, and cinematic gunplay — everything you expect from a classic GTA setup.
5. No. 1
Get ready to race through Liberty City! In this high-speed street race, Niko must prove his driving skills. It’s a thrilling ride with a killer soundtrack and tight turns that test your reflexes.
6. Final Interview
This mission is a brilliant blend of stealth and role-playing. Niko must infiltrate a law office under the guise of a job interview… but it doesn’t end with a handshake. It’s one of the more unique missions in the game.
7. Hostile Negotiation
When Niko’s cousin Roman gets kidnapped, it’s up to you to storm the warehouse and rescue him. The mission is filled with tension, close combat, and shows just how far Niko will go for family.
8. To Live and Die in Alderney
An action-packed mission with Phil Bell that includes a drug deal gone wrong and a fast-paced boat chase. It highlights the chaos and unpredictability that makes GTA IV so fun.
9. Wrong is Right
A mission filled with sniping, surveillance, and high drama. It plays like a scene from a spy thriller and shows the versatility of mission design in GTA IV.
10. Harsh Memories (The Lost and Damned)
While technically from the DLC, this mission is too good to ignore. Johnny Klebitz faces betrayal from someone close to him, leading to one of the most emotional and gritty moments in the entire GTA IV saga.
Honorable Mentions
- Truck Hustle – Action movie vibes as you jump onto a moving truck.
- Hangman’s NOOSE – A great co-op mission in multiplayer mode.
- Uncle Vlad – A pivotal early-game mission that sets the tone for Niko’s arc.
Conclusion
Whether it’s the raw emotion, the intensity of the action, or the player-driven choices, GTA IV’s missions are some of the most cinematic and immersive in the franchise. If you haven’t played these missions in a while, now’s the perfect time to revisit them and relive the legacy of Liberty City.